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CARDIOLOGY & CARDIAC SURGERY Procedure

MitraClip Percutaneous Mitral Valve Repair

MitraClip is a breakthrough catheter-based procedure that clips together the fluttering leaflets of a leaky mitral valve, eliminating severe mitral regurgitation (MR) without open-heart surgery.

MitraClip — transcatheter mitral valve repair
MitraClip — transcatheter mitral valve repair

Clinical Overview & Disease Information

MitraClip is a breakthrough catheter-based procedure that clips together the fluttering leaflets of a leaky mitral valve, eliminating severe mitral regurgitation (MR) without open-heart surgery.

Signs & Symptoms

Early Symptoms
  • Shortness of breath when lying flat (orthopnea)
  • Mild swelling in ankles and feet
Common Symptoms
  • Severe shortness of breath during minimal exertion
  • Persistent fatigue and lung congestion
  • Frequent coughing especially at night
  • Palpitations due to secondary AFib
Emergency Symptoms
  • Acute pulmonary edema with pink frothy sputum
  • Severe gasping for air

Causes & Risk Factors

Primary Causes & Etiology

  • Degenerative Mitral Valve Prolapse (MVP / Barlows Disease)
  • Functional MR secondary to Left Ventricular Dilated Cardiomyopathy
  • Ischemic Mitral Regurgitation post-heart attack

Who is at Higher Risk?

  • Surgically inoperable heart failure patients
  • Elderly patients with low ejection fraction (LVEF < 30%)

Diagnostic Evaluation & Testing

Diagnostic Test Clinical Purpose / What It Shows
3D Transesophageal Echocardiography (3D-TEE) Evaluates mitral valve grasping zone, flail segment width, and vena contracta area
Left & Right Heart Catheterization Measures pulmonary artery wedge pressure (PAWP) and cardiac output

Comprehensive Treatment Options

Percutaneous Transcatheter MitraClip G4 Edge-to-Edge Repair

Transseptal catheter insertion clips anterior and posterior mitral leaflets creating a double-orifice valve.

Key Advantages:
No sternotomy open-heart incision
Immediate reduction in mitral regurgitation
Discharge home in 2-3 days
Significant reduction in heart failure hospitalizations

Open Surgical Mitral Valve Annuloplasty & Repair

Open surgical placement of a mitral annuloplasty ring and chordal reconstruction.

Recommended For:
Surgically fit younger patients
Concomitant coronary bypass surgery required

Advanced Medical Technologies Available in Partner Hospitals

Abbott MitraClip G4 System 3D TEE Real-Time Echo Navigation Transseptal Steerable Guiding Catheter

Possible Complications If Untreated

Partial clip detachment (unclip)
Atrial septal defect persistence
Groin hematoma

Recovery Timeline, Diet & Lifestyle Care

Recovery Timeline

Procedure / Stage Expected Recovery Duration
Cath Lab Recovery & TEE Check 4 hours
Ward Mobilization 24 hours
Hospital Discharge 2 to 3 days
Return to Normal Routine 1 to 2 weeks

Recommended Post-Treatment Diet

  • Strict fluid limit (1.5L/day if heart failure)
  • Sodium restriction < 2g/day

Essential Lifestyle Changes

  • Daily weight check for fluid retention
  • Gradual walking exercise
  • Avoid strenuous lifting
When to Contact a Doctor Urgently:
Sudden weight gain > 1.5kg in 2 days
Worsening leg edema or breathlessness
Groin site bleeding

Prevention & Long-Term Health

Early medical management of dilated cardiomyopathy
ACE inhibitor & Beta-blocker therapy

Frequently Asked Questions

Does MitraClip eliminate mitral regurgitation completely?

MitraClip reduces severe 4+ MR down to mild 1+ or 2+ MR in over 90% of patients.

Can more than one clip be placed?

Yes, depending on the valve leak anatomical width, 2 to 3 MitraClips can be deployed.

Top Recommended Specialists Available

Dr. Ashok Seth

Dr. Ashok Seth

Chairman & Chief Interventional Cardiologist

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Dr. Naresh Trehan

Dr. Naresh Trehan

Chairman & Chief Cardiovascular Surgeon

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Dr. Aseem R. Srivastava

Dr. Aseem R. Srivastava

Chief – Pediatric CTVS & Chief – Adult CTVS

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Dr. Mukesh Kumar Gupta

Dr. Mukesh Kumar Gupta

Head - Critical Care (Unit III) & Heart & Lung Transplant

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Dr. Rajesh Misra

Dr. Rajesh Misra

Chairperson - Anaesthesia

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Dr. Amit Kumar Chaurasia

Dr. Amit Kumar Chaurasia

Chief Cath Lab & TAVI (Unit I)

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Dr. Biswarup Purkayastha

Dr. Biswarup Purkayastha

Consultant – Heart & Lung Transplant and Vascular Surgery

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Dr. Jeetendra Sharma

Dr. Jeetendra Sharma

Chief - Critical Care (Unit II) & Chief- Medical Quality

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Dr. (Col) Balbir Kalra

Dr. (Col) Balbir Kalra

Associate Chief - Cardiology (NIC)

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Dr. Rahul Mehrotra

Dr. Rahul Mehrotra

Chief - NIC & Clinical Cardiology

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Dr. Sameer Mehrotra

Dr. Sameer Mehrotra

Unit Chief - Interventional Cardiology & Electrophysiology

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Dr. Surendra Nath Khanna

Dr. Surendra Nath Khanna

Chairperson - Adult Cardiac Surgery & CTVS

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Dr. Sushant Mishra

Dr. Sushant Mishra

Sr. Consultant - Cardiology & Interventional Cardiology

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Dr. Kuldeep Arora

Dr. Kuldeep Arora

Unit Head & Chief Cath Lab (Unit II)

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Dr. Mukesh Kumar Gupta

Dr. Mukesh Kumar Gupta

Head - Critical Care (Unit III) & Heart & Lung Transplant Team

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Dr. Nidhi Rawal

Dr. Nidhi Rawal

Chief - Paediatric Cardiology

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Dr. Rajesh Misra

Dr. Rajesh Misra

Chairperson - Department of Anaesthesia & Perioperative Medicine

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Dr. Rati Bansal Goel

Dr. Rati Bansal Goel

Head - Critical Care (Unit III)

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Dr. Reshma Tewari

Dr. Reshma Tewari

Chief - Critical Care (Unit I)

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Dr. Shelly Mittal

Dr. Shelly Mittal

Chief - Anaesthesia & Regional Anaesthesia

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Dr. Shubhra Shri Gupta

Dr. Shubhra Shri Gupta

Principal Consultant - Neonatology & Incharge - Pediatric Cardiac Critical Care

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Dr. Swati Aggarwal

Dr. Swati Aggarwal

Principal Consultant - Anaesthesia

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Dr. Vijay Mohan Hanjoora

Dr. Vijay Mohan Hanjoora

Chief - Cardiac Anaesthesia

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Global Cost Comparison Matrix

Procedure USA (Avg) India (ISG) Turkey (Avg) Thailand (Avg)
MitraClip — transcatheter mitral valve repair $110,000 $22,000 $32,000 $35,000

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Commonly Prescribed Medications

  • Furosemide 40mg daily
  • Spironolactone 25mg
  • Sacubitril/Valsartan 49/51mg
  • Apixaban 5mg

International Patient Guide

Estimated Stay in India:
3D TEE Evaluation 1 day
MitraClip Procedure & Stay 3 days
Checkup & Return Flight 8 - 10 days total stay
Documents to Bring:
  • Passport & Visa
  • 3D TEE Echo CD & Report
  • Heart Failure Summary