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FERTILITY & REPRODUCTIVE MEDICINE Procedure

Blastocyst IVF with Controlled Ovarian Hyperstimulation

Controlled ovarian hyperstimulation (COH) with recombinant FSH/hMG, transvaginal ultrasound-guided oocyte retrieval (OPU), embryology laboratory co-incubation fertilization, and Blastocyst (Day 5) transfer under ultrasound guidance.

IVF — in vitro fertilisation
IVF — in vitro fertilisation

Clinical Overview & Disease Information

Controlled ovarian hyperstimulation (COH) with recombinant FSH/hMG, transvaginal ultrasound-guided oocyte retrieval (OPU), embryology laboratory co-incubation fertilization, and Blastocyst (Day 5) transfer under ultrasound guidance.

Signs & Symptoms

Early Symptoms
  • Inability to conceive after 12 months of regular unprotected intercourse
  • Irregular menstrual cycles (PCOS / Anovulation)
Common Symptoms
  • Low ovarian reserve (AMH < 1.2 ng/ml) or advanced maternal age (> 35 yrs)
  • Bilateral tubal factor obstruction or pelvic adhesions
  • Unexplained subfertility > 2 years
Emergency Symptoms
  • Severe Ovarian Hyperstimulation Syndrome (OHSS) with rapid weight gain & dyspnea

Causes & Risk Factors

Primary Causes & Etiology

  • Anovulatory infertility & Polycystic Ovary Syndrome (PCOS)
  • Fallopian tube blockage from past pelvic inflammatory disease
  • Diminished Ovarian Reserve (DOR) & Endometriosis

Who is at Higher Risk?

  • Couples struggling with primary or secondary subfertility seeking high success IVF blastocyst transfer

Diagnostic Evaluation & Testing

Diagnostic Test Clinical Purpose / What It Shows
Serum Anti-Müllerian Hormone (AMH) & 3D Antral Follicle Count (AFC) Accurately quantifies ovarian reserve and predicts oocyte yield
Hysterosalpingography (HSG) / HyCoSy & Diagnostic Hysteroscopy Assesses uterine cavity contour and fallopian tube patency

Comprehensive Treatment Options

Day 5 Blastocyst IVF with Ultrasound-Guided Soft Catheter Embryo Transfer

Individualized GnRH antagonist stimulation protocol, transvaginal egg retrieval, 116-hour blastocyst culture, and single euploid embryo transfer under transabdominal ultrasound guidance.

Key Advantages:
Highest clinical pregnancy rate per transfer (60-70%)
Eliminates risk of higher-order multiple pregnancies with single blastocyst transfer
Minimizes OHSS risk using agonist trigger

Frozen Embryo Transfer (FET) with Hormone Replacement Therapy (HRT)

Controlled endometrial preparation using oral estrogen and vaginal progesterone.

Recommended For:
Women at high risk of OHSS or requiring PGT-A genetic screening

Advanced Medical Technologies Available in Partner Hospitals

Time-Lapse Embryo Monitoring (EmbryoScope) Voluson 3D AFC Ultrasound Cryotop Vitrification System

Possible Complications If Untreated

Mild transient pelvic fullness
OHSS (< 2% with antagonist protocol)
Multiple gestation (< 5%)

Recovery Timeline, Diet & Lifestyle Care

Recovery Timeline

Procedure / Stage Expected Recovery Duration
Day-Care Egg Retrieval Recovery 2 to 4 hours
Day 5 Blastocyst Transfer 5 days post-retrieval
Serum Beta-hCG Pregnancy Test 12 to 14 days post-transfer

Recommended Post-Treatment Diet

  • High protein recovery diet (eggs, paneer, fish, legumes)
  • Hydration 3.0L water/day

Essential Lifestyle Changes

  • Avoid strenuous exercise or heavy lifting > 5kg after embryo transfer
  • Strict daily adherence to prescribed progesterone luteal support
  • Avoid hot baths or saunas
When to Contact a Doctor Urgently:
Sudden weight gain > 1kg/day with abdominal distension (OHSS warning)
Severe pelvic pain or heavy vaginal bleeding
Shortness of breath

Prevention & Long-Term Health

Early ovarian reserve screening (AMH test) for women over 30 planning future family

Frequently Asked Questions

Is IVF egg retrieval painful?

No, transvaginal egg retrieval is performed under short intravenous conscious sedation, ensuring complete comfort throughout the 15-minute procedure.

Top Recommended Specialists Available

Dr. Renu Raina Sehgal

Dr. Renu Raina Sehgal

Chairperson - Department of Obstetrics & Gynaecology

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Dr. Nidhi Jain

Dr. Nidhi Jain

Sr. Consultant - Obs & Gynae

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Dr. Nutan Agarwal

Dr. Nutan Agarwal

Head of Department - Gynae Endocrinology & DNB Program Director

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Dr. Deepa Maheshwari

Dr. Deepa Maheshwari

Sr. Consultant - Obstetrics & Gynaecology

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Dr. Kiran Arora

Dr. Kiran Arora

Unit Head - Reproductive Medicine & IVF (Unit II)

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Dr. Nidhi Rajotia (Goel)

Dr. Nidhi Rajotia (Goel)

Unit Head - Obs & Gynae

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Dr. Renu Raina Sehgal

Dr. Renu Raina Sehgal

Chairperson - Department of Obstetrics & Gynaecology

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Dr. Sarabpreet Singh

Dr. Sarabpreet Singh

Head - Clinical Embryology & Andrology

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Dr. Seerat Sandhu

Dr. Seerat Sandhu

Classified Consultant - Obstetrics & Gynaecology

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Dr. Deepika Aggarwal

Dr. Deepika Aggarwal

Chief - Laparoscopic Gynae & Robotic Surgery

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Global Cost Comparison Matrix

Procedure USA (Avg) India (ISG) Turkey (Avg) Thailand (Avg)
IVF — in vitro fertilisation $18,000 $3,200 $5,200 $6,000

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Commonly Prescribed Medications

  • Recombinant FSH (Gonal-F)
  • Cetrotide 0.25mg
  • Ovidrel 250mcg Trigger
  • Micronized Progesterone 400mg

International Patient Guide

Estimated Stay in India:
AMH & Follicular Scan Workup 1 - 2 days
Ovarian Stimulation & Egg Retrieval (OPU) 10 - 12 days
Blastocyst Transfer & Return Flight 15 - 18 days total stay
Documents to Bring:
  • Couple Passports & Marriage Certificate
  • Previous Hormone & Semen Reports