Nintedanib Anti-Fibrotic & Bosentan Dual PAH Therapy
Nintedanib anti-fibrotic therapy, Bosentan, and Sildenafil for Systemic Sclerosis (SSc) ILD & digital ulcers.
Clinical Overview & Disease Information
Nintedanib anti-fibrotic therapy, Bosentan, and Sildenafil for Systemic Sclerosis (SSc) ILD & digital ulcers.
Signs & Symptoms
- • Early autoimmune symptoms
- • Mild Skin tightening on hands/face, Raynaud's phenomenon (white/blue fingers), shortness of breath
- • Persistent Skin tightening on hands/face, Raynaud's phenomenon (white/blue fingers), shortness of breath
- • Joint swelling or skin changes
- • Systemic fatigue & inflammation
- • Organ-threatening flare, severe vasculitis, or alveolar hemorrhage
Causes & Risk Factors
Primary Causes & Etiology
- Systemic Sclerosis (Scleroderma) & SSc Interstitial Lung Disease
- Autoimmune dysregulation & autoantibody production
- Genetic HLA susceptibility
Who is at Higher Risk?
- Patients diagnosed with Systemic Sclerosis (Scleroderma) & SSc Interstitial Lung Disease
- Individuals requiring specialized biological immunotherapy
Diagnostic Evaluation & Testing
| Diagnostic Test | Clinical Purpose / What It Shows |
|---|---|
| ANA Autoantibody Profile & MSK Ultrasound for Scleroderma management | High-sensitivity serological profiling and structural joint evaluation |
Comprehensive Treatment Options
Targeted Biologic / Immunosuppressive Protocol for Scleroderma management
Board-certified rheumatologist & immunologist executed procedure.
Multidisciplinary Autoimmune Care for Scleroderma management
Comprehensive pulse steroid or autologous stem cell protocol.
Advanced Medical Technologies Available in Partner Hospitals
Possible Complications If Untreated
Recovery Timeline, Diet & Lifestyle Care
Recovery Timeline
| Procedure / Stage | Expected Recovery Duration |
|---|---|
| Infusion / Injection Recovery | 1 to 4 hours |
| Reduction in Inflammatory Pain | 1 to 2 weeks |
| Target Clinical Remission | 3 months |
Recommended Post-Treatment Diet
- Anti-inflammatory Mediterranean diet
- Hydration 2.5L/day
Essential Lifestyle Changes
- Perform daily low-impact hydrotherapy exercises
- Strict adherence to prescribed medication schedule
Prevention & Long-Term Health
Frequently Asked Questions
What is the goal of treatment for Scleroderma management?
The main goal is inducing complete disease remission, stopping joint erosion, and restoring active living under board-certified rheumatologists.
Top Recommended Specialists Available
Dr. Namita Jaggi
Chairperson- Lab Services and Infection Control & Chief- Education & Research
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Dr. Namita Jaggi
Chairperson - Lab Services & Infection Control; Chief - Education & Research
View Doctor Profile →
Global Cost Comparison Matrix
| Procedure | USA (Avg) | India (ISG) | Turkey (Avg) | Thailand (Avg) |
|---|---|---|---|---|
| Scleroderma management | $25,000 | $4,500 | $6,500 | $7,500 |
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Get Free Treatment EstimateCommonly Prescribed Medications
- Biologic bDMARDs
- Methotrexate
- Targeted Steroids
International Patient Guide
- Passport & Visa
- ANA / Autoantibody Reports & Joint X-Rays